Antiulcer activity of medicinal plants pdf files

Antiulcer activity was evaluated by measuring ulcer index and percentage of ulcer healing. Antiinflammatory and antioxidant activities of medicinal. Many medicinal plants exhibit antiulcer activity and found useful in the treatment of peptic ulcer. Medicinal plants used in folk medicine contain a wide range of substances that can prevent and treat many diseases. Antioxidant activity and constituents of propolis collected in various areas of china. Ulcer was induced by administering 1 ml of absolute histamine acid phosphate solution 50 mg base i. Antiulcer activities of medicinal plants and natural. The observed activity is these plants is attributed with the presence of flavonoids, alkaloids, terpenoids, tannins, saponins, and phenolic acids 4, 10, 15, 21. Plants as natural antiinflammatory agents unlike modern allopathic drugs which are single active components that target one specific pathway. The purpose of this study was the evaluation by a chemical method of the antioxidant capacity of phenolic compounds in some algerian medicinal plants. Dhanapalan college of arts and science, chennai, india. This was done to verify its ethno medicinal use in the treatment of ulcer. In spite of being one of the wellknown medicinal plants used inindian traditional medicine to treat several ailments, studies pertaining to the pharmacologicalproperties of some medicinal plants are very scarce. Treatment of peptic ulcers depends on using a number of synthetic drugs that reduce.

We had studied at the medical college, trivandrum, properties of nimbidine, the bitter amorphous. Exploring indian medicinal plants for antiulcer activity p. The structures and biological activities of the bark and leaf pectins were therefore compared in order to make recommendation on plant part substitution as debarking can damage or even kill the tree. It has been documented that a great amount of traditional knowledge about the uses of medicinal plant. Free radical scavenging activity and total phenolic compounds of. Traditionally the plant is reported to have antiulcer activity. The extract was evaluated for its free radical scavenging activity by dpph method followed by antiulcer activity using pyloric ligation, water immersion stress and nsaid indomethacin induced gastric ulcer model niu in rats. An illustrated, scientific and medicinal approach appears to be a medical compendium of plants intended as a guide and reference resource for professionals in the field. In this context, it is largely known the folk use of medicinal plants in the treatment of gastric ulcers. We studied the antiulcer activity and acute toxicity of some medicinal plants. Acalypha indica can be useful in treating pneumoniae, asthma, rheumatism and several other ailments.

Drugs of plant origin are gaining popularity and are being investigated for a number. Medicinal plants as antiulcer agents pharmacognosy journal. Consequently we have evaluated the anti ulcer activity of meaf. Vidya ignatius, 1 madhusudhanan narayanan, 1 venkataraman subramanian, 2 and balasubramanian maruthaiveeran periyasamy 2 1 department of pharmacology, sathyabama university dental college and hospital, sathyabama university, jeppiaar nagar, rajiv gandhi road, chennai.

The total alkaloids content tac was evaluated according to the chloride colometric method in which atropine was. Fam family, t tree, h herb, c climber, s shrub plant common name maturity period botanical name or family parts used average price rs. Evaluation of antiulcer activity of the leaf extract of osyris. Currently medicinal plants have become the paramount source of drug discovery in research for treating diverse form of diseases including cancer. Exploring indian medicinal plants for antiulcer activity.

However, these drugs have shown disease relapse, side effects, and even drug interactions. Evaluation of antiulcer activity of moringa oleifera seed extract. The current study aimed to investigate the polyphenol content in some of these medicinal plants and to. The final volume of franz eugen kohlers medizinalpflanzen or medicinal plants published in 1887 features red algae and fungi too. An aphrodisiac is defined as an agent that arouses sexual desire. Antiulcer activity of ethanolic extract of salvadora. Gastric ulcers are located in the stomach, characte rized by pain.

Antiulcer activity of some selected medicinal plants. As high as 80% of the world population depends on plantderived medicines for the first line of. The potential medicinal plants used in ulcer in spite of being one of the wellknown medicinal plants used in indian traditional medicine to treat several ailments, studies pertaining to the pharmacological properties of some medicinal plants are very scarce. Antiulcer antiulcer allophylus pdf antiulcer therapeutics has wider market globally citing the fact of prevalence of. Rana, nidhi sharma and sunil kumar abstract a peptic ulcer is an erosion in a segment of the gastro intestinal mucosa, typically in the stomach gastric ulcer or first few centimeters of duodenum duodenal ulcer that penetrates through the muscularis mucosae. In recent times, focus on plant research has increased all over the world and a large body of evidence has collected to show immense potential of medicinal plants used in various traditional systems. A potential of some medicinal plants as an antiulcer agents. Aroma is offering an ineffable support to the folk medicine, which is a traditional medicine for the treatment of ulcers in india. Evaluation of antiulcer activity of boswellia serrata bark. Traditional medicine and drug discovery 80% of the world population resides in developing countries 80% of people in developing countries utilize plants to meet their primary health care needs global pop. Peptic ulcer, gastric ulcer, aggressive factors, defensive factors, abdominal pain, medicinal plants. This association of medicinal plants and cancer needs further research and experimentation in order to develop and design anticancer drugs. Exploring indian medicinal plants for antiulcer activity bioline. The extract at 400 mg kg1 and 600 mg kg1 showed significant 0.

In this present work, antiulcer effect of different extracts of physalis minima was studied in. Antiulcer activity of pisonia aculeata on pylorus ligation. But these drugs are expensive and are likely to produce more side effects when compared to herbal medicines. Active principles of antiulcer activity are flavonoids, terpenoids and tannins. The parameters assessed were gastric volume, free acidity, total acidity, ulcer index and percentage ulcer protection. Medicinal plants naturally synthesize and accumulate some secondary metabolites, like alkaloids, sterols, terpenes, flavonoids, saponins, glycosides, cyanogenics, tannins, resins. Antiulcer activities of commiphora molmol myrrh extract. Generating an epub file may take a long time, please be patient. We conclude that plant extracts are potential sources of new antiulcer agents.

Gastric ulcers are located in the stomach, characterized by pain. Abstract the recent pharmacological studies showed that many medicinal plants exerted a wide range of beneficial gastrointestinal effects. It has mucoprotective activity and gastric antisecretary when compared with that of reference drugs. Ittiyavirah masters thesis medicine pharmacology publish your bachelors or masters thesis, dissertation, term paper or essay. Components in the methanolic extract of plants revealed by hplc analysis. Ag is a famous medicinal plant widely used for its medicinal properties for the treatment of many diseases such as dysentery, hepatitis. The antiulcer activities effects of myrrh or commiphora molmol extract cme were assessed in rats. Indian medicinal plants, peptic ulcer, ocimum sanctum. Invivo gastric antiulcer activity of syringin phenyl propanoid glucoside studied in different ulcer induced experimental rat models c.

Antiulcer activity of indigenous plant operculina turpethum linn. Evaluation of antiulcer activity of the main phenolic acids found in brazilian green propolis. Some medicinal plants used in the treatment of ulcer. Hplc analysis of phenolic compounds was done using methanol and water as mobile phase at 254 nm. The antiulcer activity of the methanolic extract of kigelia africana was evaluated in wistar albino rats. A potential of some medicinal plants as an antiulcer agents ncbi. P, 2 sri sai college of pharmacy, badhani, pathankot145001.

According to traditional and ethnomedicinal claims. Gastric fluid total acidity and free acidity were estimated in pylorus ligated rats. The antiulcer activity of esil 150, 300 and 600 mgkg p. The petroleum ether 250mgkg and aqueous extracts 250mgkg of bark of boswellia serrata plant showed significant antiulcer activity as evifindings also confirm the antiulcer activity of boswellia serrata bark extracts in albino rats. Structures, and immunomodulating and antiulcer activities. Various herbal plants and plants extracts have significant antiulcer activity in animal models. The anti gastric ulcer activity of pisonia aculeata leaf extracts in pylorus ligation model is evident from its significant reduction in gastric volume, free acidity, total acidity, ulcer score and increase in p h when compared to that of standard drug. The medicinal chemistry course adme adsorption, distribution, metabolism and excretion of drugs drugreceptor interactions development of drugs screening techniques combinatorial chemistry d. A total of 25 plants belonging to different species of leguminosea family. Pdf antiulcer activity of some indian medicinal plants. About jmpr the journal of medicinal plant research is published weekly one volume per year by academic journals. Over the last few years, rechears have aimed at identifying and validating plant derived substances for the treatment of various diseases. In case of the rest of the medicinal plants the 2008, serotonin and egg. Phenolic compounds are commonly found in both edible.

This third volume contains an additional collection of 32 monographs describing the quality control and use of selected medicinal plants. Ayurvedic knowledge supported by modern science is necessary to isolate, characterise, and standardise the active constituents from herbal sources for antiulcer activity. The journal of medicinal plants research jmpr is an open access journal that provides rapid publication weekly of articles in all areas of medicinal plants research, ethnopharmacology, fitoterapia, phytomedicine etc. The literature revealed that many medicinal plants. Antiulcer activity of aetp was studied in rats in which gastric ulcers were induced by oral administration of ethanol or 0. Several researches have confirmed the efficacy of medicinal plants for the treatment of peptic ulcer disease. A number of drugs including proton pump inhibitors and h 2. Acidic heteroxylans from medicinal plants and their antiulcer activity. There are various medicinal plants and their extracts containing active chemical constituents, e. But the nature lovers that we are, we have left them in.

The petroleum ether 250mgkg and aqueous extracts 250mgkg of bark of boswellia serrata plant showed significant antiulcer activity as evidenced by the data obtained. The mechanism involved in production of antiulcer activity of the plant is due to its antioxidant, antiinflammatory, mucus. Antiulcer activity of ficus religiosa leaf ethanolic extract. See previous posts for volume 1, volume 2 and volume 3 with associated book and source details. The white mulberry has a long history of medicinal use in.

Although medicinal plants are generally safe when used appropriately according to the traditional methods, some are inherently toxic. A person may have both gastric and duodenal ulcers at the same time. Introduction increasing role of the who monographs on selected medicinal plants over the past two decades, there has been a tremendous increase in the use of herbal medicine. Thus, there is an urgent need to identify more effective and safe antiulcer agent. The peptic ulcer is a widespread and common health problem around the world. Herbal drugs with anti ulcer activity dilpreet kaur, a. The extract is nontoxic even at relatively high concentrations. The mechanism involved in production of antiulcer activity by plant leaf extract is cytoprotective mechanism as well as antisecretory 8. The antiulcer activity of the poly herbal formulation composed of the leaf extracts from lantana camara, annona muricata, kalanchoe pinnata was evaluated in stress induced ulcer model in rats. In this context, the use of medicinal plants for the prevention and treatment of different pathologies is in continuous expansion worldwide 10. Pdf antiulcer activity of some selected medicinal plants. Phytochemical importance of medicinal plants as potential. Medicinal plants containing active chemical constituents are useful in prevention and treatment of. Antiulcer activities of medicinal plants and natural products.

Hence several experimental studies have demonstrated that medicinal plants extracts are important sources for chemical compounds with gastroprotective activity 9. Histological studies revealed that these medicinal plants did not show any acute toxicity. Antinociceptive activity was evaluated in acetic acidinduced writhing, formalin and tail immersion tests in mice while antiulcer activity was evaluated. In order to enhance the use of plants as potential sources of new therapeutic agents and to advocate. In pyloric ligation induced ulcer model, the studied parameters were gastric volume, ph, total acidity, free acidity, and ulcer index whereas in ethanol and cysteamine induced ulcer model, the ulcer index was determined for severity of ulcers.

Medicinal plants and traditional medicines in africa. Medicinal plants as antiulcer agents t lakshmi srinivas, s mohana lakshmi, s neelufar shama, g koteswara reddy. Invivo gastric antiulcer activity of syringin phenyl. A large number of populations are now relying on these medicinal plants as they are relatively safe, cheap and have no adverse effects. Antiulcer activity of different extracts of anvillea garcinii and. Antiulcer screening of selected plants of plumbago species and the effect of plumbagin in gastric cell lines studies of plumbago plants for ulcer and inflammation treatment dr. This article will be concerned only with the antiulcer and gastroprotective effects. In addition, inappropriate use wrong plant parts, dose, frequency, route of administra tion, preparation, etc. Preliminary photochemical screening of this medicinal plant identified the presence of important secondary metabolites like flavonoids and tannins which are the active principles of antiulcer activity. Antinociceptive and antiulcer activities of pycnanthus. To study the antiulcer activity of aqueous extract of roots of tephrosia purpurea aetp using different models of gastric and duodenal ulceration in rats.

Evaluation of antiulcer activity of whole plant extract of malvastrum. The major causes include generation of free radicles, decrease in mucosal defense. Comparative phytochemical analysis of selected medicinal. Evaluation of free radical scavenging and antiulcer. In vitro antioxidant capacity and in vivo antiulcer and. Biogeographic regions see more details for peptic ulcer and, if reported, the antiulcer activity. Analgesic, antipyretic and antiulcer activities of ailanthus. Date ddmm a potential of some medicinal plants as an. The plant leaf extracts reported antiulcer activity in experimentallyinduced gastric ulcers in rats. Medicinal plants provide an effective and safer way in disease management. As herbal medicines are considered as safe for the treatment of ulcers with lesser adverse effects, economical, effective, relatively less toxic, extensive research is carried out in search for potent antiulcer agents of plant origin. Dglucopyranosyloxyethane was isolated natutally first time from the annona squamosa twigs. Physalis minima has shown antiinflammatory and analgesic action in animals. Kg medicinal use amla t after 4th year emblica officinalis fam euphorbiaceac fruit rs 15 45kg vitamin c, cough.

Total alkaloids, tannin content, and antiulcer assay of. Antioxidant activity of some algerian medicinal plants. Pdf acidic heteroxylans from medicinal plants and their. Palit abstract peptic ulcer disease pud is a serious gastrointestinal disorder that requires a well tar geted therapeutic strategy.

To my delight and i am sure of anyone who picks up this book, i discovered it contains nug. Hence, it establishes the fact that the methanol extract of antiulcer activity of acacia farnesiana l. Swingle is a decidous tree belonging to simaroubaceae family and widely distributed in asia and north australia. Antiulcer screening of selected plants of plumbago species. These medicinal plants showed stronger antioxidant activity and content in phenolics than the common nutritional plants. Evaluation of the antiulcer properties of castor plants. Also, ethnomedical systems employ several plant extracts for the treatment of peptic ulcer. Gymnema sylvestre is a highly valued ethno pharmacologically important medicinal plant used currently in many polyherbal formulations due to its potential antidiabetic activity and other health benefits. Antiulcerogenic activity of ethanol extract of the bark from. The medicinal plants have been used for treatment of illnesses and diseases, since the dawn of time. The information is recorded in plant scientific name, family, part used, route of administration, dose given, method used. The underlisted medicinal plants have been pharmacological reported to possess antiulcer activity as previously compiled3435363738 39.

Therefore, efforts should be directed towards isolation and characterization of the active principles and elucidation of the relationship between structure and activity. Who published volume 1 of the medicinal plants, containing. The present study was carried out to analyze the antistress, antiallergic, and antiulcer activity of the bioactive. The in vivo bioassay was conducted on formalin mosaddek et al. The antigastric ulcer activity of 90% ethanolic extract at 200mgkg is.

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